11,350,824 papers found

BACKGROUND: Selective constraint, the depletion of variation due to negative selection, provides insights into the functional impact of variants and disease mechanisms. However, its characterization in mice, the most commonly used mammalian model, remains limited. This study aims to quantify mouse gene constraint using…

OBJECTIVES: Excessive Internet use is a health concern among higher education students leading to reduced academic performance and problems in everyday life. This study aimed to explore the relationship between health and problems of studying and daily rhythm caused by time spent online among students (n=3,050). METHO…

INTRODUCTION: Degeneration of the intervertebral disc (IVD) is a frequent cause for back pain in humans and dogs. Link-N stabilizes proteoglycan aggregates in cartilaginous tissues and exerts growth factor-like effects. The human variant of Link-N facilitates IVD regeneration in several species in vitro by inducing Sma…

OBJECTIVES: This study's objective consisted of the construction and validation of a scale to identify the representation of human vulnerability in the health field. METHOD: its development was divided into three steps: a bibliographic review and exploratory interviews were conducted to establish the items and their s…

OBJECTIVE: Pain management is a cornerstone of osteoarthritis (OA) management. The aim of this review is to obtain current, literature-based estimates of the effect of common pharmacologic treatments on pain reduction in OA. METHODS: A MEDLINE search (2006-2016) was conducted for randomized controlled trials studying…

Despite the widespread use of modern social media, relatively less is known about the impact of social media on the acculturation processes of international students in China and their engagement in school activities. Accordingly, this research intends to assess the influence of social media usage while answering quest…

Studies investigating the potential structures underlying the connection between mindfulness and romantic relationship quality are not sufficient and require additional empirical findings. The current study aimed to examine a hypothesized model underlying the association between mindfulness and relationship quality, wh…

This article introduces the design principles of a web-based assistive technology (WAT) developed for students with visual impairment (VI). The pedagogical goal guiding the development process was the enhancement of vocabulary knowledge for students studying English as a foreign language (EFL) in terms of their spellin…

Music and speech are encountered daily and are unique to human beings. Both are transformed by the auditory pathway from an initial acoustical encoding to higher level cognition. Studies of cortex have revealed distinct brain responses to music and speech, but differences may emerge in the cortex or may be inherited fr…

OBJECTIVE: This article describes the steps in the planning and development of the 2002 Feeding Infants and Toddlers Study. METHODS: We describe the study's rationale, sampling methodology, survey questionnaire development, dietary methodology, field data collection, and data processing and analysis. A brief review of…

BACKGROUND: Replication study is a commonly used verification method to filter out false positives in genome-wide association studies (GWAS). If an association can be confirmed in a replication study, it will have a high confidence to be true positive. To design a replication study, traditional approaches calculate pow…

The article by Keaveney et al. entitled 'Effects of acetaminophen on risk taking' was published in July of 2020 and concluded that using acetaminophen increased risk-taking behaviors, potentially by reducing perceived risk. We believe that there is not enough data to support the generalization of this association…

The purpose of this study was to determine the center of mass of the trunk in living subjects by using computed tomography (CT), thus providing more accurate data to aid scientists in their effort to describe human motion quantitatively. This advanced x-ray was used to analyze the trunk segment of four subjects, two me…

The study's purposes were, by analyzing all Journal of Biomechanics publications from one year in each of six decades, to quantify in those published studies 1) the contribution of female authors, 2) the inclusion of female participants, and 3) if female or male authors were more likely to conduct studies with only fem…

Single-case researchers often implement multiple-baseline designs as their preferred methodology for intervention evaluations. Recent writings and empirical investigations have argued in favor of incorporating various forms of randomization into such designs for the purpose of elevating the intervention study's interna…

Researchers who study the central nervous system (CNS) face special challenges in notifying study participants about the research results. There are human research guidelines regarding the communication of information to subjects at the outset of a CNS research study. Yet there are few guidelines on how to communicate…

The time after diagnosis of a terminal illness can be demanding. It requires adjusting to change while trying to maintain some sense of normalcy. The purpose of this qualitative case study was to gain an understanding of how one person lived his life while facing death. During the interview, the researchers used photo…

When exploring the landscape of leadership learning in study abroad, it is critical to understand the leadership learning that takes place through short-term study abroad courses. This article will provide a definition of short-term study abroad and short-term study abroad leadership courses through an overview of rele…

Brewis, Workman et al. (2020) provided a basis for significant subsequent advancement in understanding the interplay between household water insecurity and food insecurity across diverse global contexts. This commentary reflects on the subsequent evolution of research and its application in the 5 years sinc…

Hydatidosis or cystic echinococcosis (CE) is one of the most common zoonosis diseases. Iran is one of the endemic regions in terms of this disease. For the first time, the present study was conducted to determine the seroprevalence of hydatid cyst in Zahedan rural areas due to the importance of human CE and lack of inf…