5,081,869 papers found

A reduction in sedentary behavior (SB) can contribute to the prevention of chronic diseases. This is the first umbrella review that summarizes the effectiveness and monetary costs of different types of interventions to reduce SB across all age groups and populations in different settings. We comprehensively searched se…

AIM: This systematic review of reviews aims to critically evaluate and synthesize findings from recent systematic reviews to analyze the effectiveness of transitional care interventions in the management of adult patients with chronic illnesses. BACKGROUND: Transitional care interventions have been provided to patient…

OBJECTIVES: We aimed to map the systematic review evidence available to inform the optimal prescribing of statins and antihypertensive medication. DESIGN: Systematic umbrella review and evidence and gap map (EGM). DATA SOURCES: Eight bibliographic databases (Cochrane Database of Systematic Reviews, CINAHL, EMBASE, He…

AIMS: Synthesize a review of reviews of the family's role in supporting adherence to diabetes self-care management practices (DSMP) for adults with type 2 diabetes (DM2). DESIGN: An umbrella review. DATA SOURCES: Scopus, Web of Science including MEDLINE, CINAHL via EBSCO, PubMed and Science Direct were searched for s…

Accurate assessment of postural balance is necessary to identify and measure falls risk, inform clinical practice, determine efficacy of treatment and ultimately falls prevention. The aim of this scoping review was to identify gaps and inform practice, research and policy. There are a multitude of technologies availabl…

Otolaryngology residents would benefit greatly from undertaking systematic reviews of knowledge during training. Undertaking a systematic review allows for the acquisition of skills in electronic searching, research methodology, critical appraisal, and statistical analysis. Even when reviews have inconclusive findings,…

OBJECTIVES: Formaldehyde is an organic compound used in the production of resins, paper, wood plywood, solvents and cleaning products. Formaldehyde is also present when tobacco is smoked. Formaldehyde has been defined as an irritant and is classified as a human carcinogen by the International Agency for Research on Can…

BACKGROUND: Acting on social determinants is the most effective, efficient, and fairest strategy to improve population health and health equity. Because of their vulnerability and dependence, children are particularly exposed to the deleterious effects of their living environment. Taking these issues into account in th…

OBJECTIVE: There are many systematic reviews of weight management interventions delivered by healthcare professionals (HCP), but it is not clear under what circumstances interventions are effective due to differences in review methodology. This review of systematic reviews synthesises the evidence about: (a) the effect…

AIMS AND OBJECTIVES: To establish how common and impactful nursing and healthcare ageism is and whether proven interventions or prevention methods exist. BACKGROUND: Ageism has been a concern since 1969 when it was first introduced as a concept for social reform. As ageism has been linked to lower quality health servi…

BACKGROUND: A growing body of research is addressing the process and science of engaging people with lived experience (PWLE) of mental health challenges and other psychiatric conditions, and family members, in research activities. OBJECTIVE: This scoping review of reviews synthesizes literature reviews on the engageme…

BACKGROUND: Minor impact soft tissue (MIST) is an insurance industry concept that seeks to identify late whiplash as a psychosocial phenomenon. However, the medical literature in this area has not been systematically reviewed since the Quebec Task Force's review in 1995. OBJECTIVE: To review the medical literature whi…

Even though exposure to chlorine gas has been quite frequent in the past few decades, no specific antidotes exist. This umbrella review aimed to investigate possible recommendations for treatment after a chlorine gas exposure. A published systematic review protocol that adapted the existing Navigation Guide methodology…

The main objective of this umbrella review is to synthesise available evidence from systematic reviews on the effectiveness of interventions for the management of occlusions in central venous access devices. CVADS have been extensively utilised among the critically ill since the 1950s however have also been linked to a…

OBJECTIVES: Our main objective is to assess the inter-reviewer reliability (IRR) reported in published systematic literature reviews (SLRs). Our secondary objective is to determine the expected IRR by authors of SLRs for both human and machine-assisted reviews. METHODS: We performed a review of SLRs of randomised cont…

The amount of available biomedical information is vast and growing. Natural limitations of the way clinicians and researchers approach this treasure trove of information comprise difficulties locating the information, and once located, cognitive biases may lead to inappropriate use of the information. Systematic review…

BACKGROUND: Research waste is present in all study designs and can have significant consequences for science, including reducing the reliability of research findings and contributing to the inefficient use of resources. Estimates suggest that as much as 85% of all biomedical research is wasted. However, it is uncertain…

OBJECTIVE: Effective interventions are needed to mitigate effects of stress and anxiety from conception and up to two years postpartum (the first 1000 days), but it is unclear what works, for what populations and at what time points. This review aimed to synthesise evidence from existing reviews of the effects of stres…

Although some studies have suggested a strong relationship between religion and spirituality (R&S) and patient outcomes in cancer care, other data have been mixed or even noted adverse effects associated with R&S in the healthcare setting. We sought to perform an umbrella review to systematically appraise and synthesiz…

It is widely recognised that findings from experimental studies should be replicated before their conclusions are accepted as definitive. In many research areas, synthesis of results from multiple studies is carried out via systematic review and meta-analysis. Some fields are also moving away from null hypothesis signi…