5,082,504 papers found

OBJECTIVE: To conduct a systematic review of systematic reviews and national guidelines to assess the effectiveness of four treatment approaches (manual therapy, probiotics, proton pump inhibitors and simethicone) on colic symptoms including infant crying time, sleep distress and adverse events. METHODS: We searched P…

INTRODUCTION: Umbilical hernia is a common pediatric disorder that pediatric surgeons are usually asked to manage. Most cases will be closed spontaneously during the first 4-5 years of life. Low number of studies regarding umbilical defects in children does not allow a definitive guideline to be drawn about their natur…

OBJECTIVES: The aim of the study was to assess the completeness of reporting of methods in overviews. STUDY DESIGN AND SETTING: Assessment of the adequacy of reporting of methods in a random sample of 50 overviews was based on a published framework of methods for conducting overviews. Descriptive summary statistics we…

OBJECTIVES: Patient flow and crowding are two major issues in ED service improvement. A substantial amount of literature exists on the interventions to improve patient flow and crowding, making it difficult for policymakers, managers and clinicians to be familiar with all the available literature and identify which int…

OBJECTIVES: To evaluate which are the most effective procedures to maintain and recover soft tissue health around dental implants. DATA SOURCES: The Cochrane Oral Health Group's Trials Register, CENTRAL, MEDLINE and EMBASE were searched with no language restriction up to June 2007. Handsearching included several denta…

Inflexible use of evidence hierarchies confuses practitioners and irritates researchers. So how can we improve the way we assess research?

OBJECTIVE: The objective of this review was to provide an overview of technologies (devices, tools, or software applications) used to facilitate remote rehabilitation of adults with deconditioning, musculoskeletal conditions, stroke, or traumatic brain injury, and to summarize the quantitative evidence of their efficac…

BACKGROUND: Medication errors are one of the leading avoidable sources of harm to hospital patients. In hospitals, a range of interventions have been used to reduce the risk of errors at each of the points they may occur, such as prescription, dispensing and/or administration. Systematic reviews have been conducted on…

AIM: A systematic review of reviews was conducted to identify and appraise brief measures of health-related quality of life (HRQoL) that have been used in peer-reviewed research with people living with HIV. METHODS: The review was conducted in two stages: 1) search of electronic databases to identify systematic r…

We conducted an umbrella review to synthesize the evidence on the effectiveness of interventions incorporating wrist-worn wearables' feedback on diverse health outcomes including health promotion (i.e., health behaviors and disease risk perception) morbidity, mortality, functioning, and other health-related metrics in…

CONTEXT: Numerous randomized controlled trial (RCT) meta-analyses have shown how beneficial probiotics are for a variety of health conditions. To date, to our knowledge, however, there has not been any synthesis of the overall strength and caliber of this evidence. OBJECTIVE: The objective is to evaluate the quality o…

OBJECTIVE: To identify the most commonly reviewed behaviour change techniques (BCTs) and their effectiveness based on consistency across reviews for lifestyle interventions of non-communicable diseases. DESIGN: Umbrella review of systematic reviews. DATA SOURCES: PubMed, Embase, PsycINFO, Cochrane CENTRAL, Global Hea…

BACKGROUND: The role of echocardiography in the diagnostic and prognostic assessment of pulmonary hypertension (PH) has been widely studied recently. However, these findings have not undergone normative evaluation and may provide confusing evidence for clinicians. To evaluate and summarize existing evidence, we perform…

BACKGROUND: Emerging evidence supports the health benefits of ginger for a range of conditions and symptoms; however, there is a lack of synthesis of literature to determine which health indications are supported by quality evidence. OBJECTIVES: In this umbrella review of systematic reviews we aimed to determine the t…

BACKGROUND: Major depressive disorder (MDD) is a common mental problem and one of the leading causes of disability worldwide. SSRIs are the most commonly prescribed types of antidepressants which are called Selective Serotonin Reuptake Inhibitors and used as a primary therapeutic intervention in MDD. This umbrella revi…

AIM: To present an overview of effective interventions for quality improvement in primary care at the practice level utilising existing systematic reviews. BACKGROUND: Quality improvement in primary care involves a range of approaches from the system-level to patient-level improvement. One key setting in which quality…

TOPIC: A synthesis of the current knowledge on risk factors for primary open-angle glaucoma (POAG). CLINICAL RELEVANCE: This review advances understanding, guides future research, and informs strategies for preventing and treating POAG. METHOD: We conducted a systematic search of PubMed, Embase, Web of Science, and t…

BACKGROUND: Young people are disproportionately more likely than other age groups to use substances. The rise in substance use and related harms, including overdose, during the Covid-19 pandemic has created a critical need for more innovative and accessible substance use interventions. Digital interventions have shown…

We conducted a comprehensive survey of Foods with Function Claims (FFC) submitted from April to August 2022 to examine the scientific reliability of the systematic review (SR), which is the basis for functional claims. The results of the review of 611 functional claims for 398 products showed that there were 121 functi…