375,956 papers found

Four randomized clinical trials comparing cyclophosphamide plus cisplatin (CP) versus cyclophosphamide, doxorubicin, and cisplatin (CAP) individually failed to show a significant survival difference in the treatment of ovarian carcinoma. However, by pooling 1,194 patients from these trials in a meta-analysis, there is…

The value of antibiotic prophylaxis in abdominal hysterectomy was reviewed by meta-analysis. Two independent literature searches (1986-1988) yielded 150 relevant papers, however, only 17 (11.3%) papers met our inclusion criteria. The selected papers described prospective, randomized, blinded, placebo-controlled studies…

AIMS: (i) To summarize the application scenarios and teaching models of AI and VR in healthcare education. (ii) To compare teaching outcomes between AI, VR, and traditional methods. (iii) To identify the relative advantages of AI and VR in different outcomes. DESIGN: A network meta-analysis. DATA SOURCES: We systemat…

OBJECTIVE: To determine whether low protein diets retard the development of end stage renal disease. DESIGN: Meta-analysis of 46 trials since 1975, from which six randomised controlled trials were selected. SETTING: Five trials in Europe and one in Australia between 1982 and 1991. SUBJECTS: 890 patients with mild to…

BACKGROUND: The effectiveness of endoscopic transpapillary gallbladder drainage (ETGBD), percutaneous gallbladder drainage (PTGBD), and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) for treating acute cholecystitis in individuals with elevated surgical risk is not yet thoroughly evaluated. METHODS: The c…

BACKGROUND: Insomnia is a common problem after a stroke, affecting daily life and the recovery process. Among the many Traditional Chinese Medicine(TCM) nursing techniques, it is still unknown which measures are most effective. OBJECTIVE: To evaluate the efficacy of different TCM nursing techniques on post-stroke inso…

BACKGROUND: The treatment strategies and efficacy of medication-related osteonecrosis of the jaw (MRONJ) are controversial, and there is a lack of unified clinical treatment standards. We used a Bayesian network meta-analysis method to evaluate the clinical efficacy of different intervention methods. METHODS: We searc…

Developmental change in twin similarity was examined with age contrasts in a meta-analysis of twin studies from 1967 through 1985. Intraclass rs were coded from 103 papers that included data for monozygotic or dizygotic twins, or for both, on personality or intelligence variables. Analyses indicated that there was a ge…

Replacement therapy with surfactant extracts in premature infants with respiratory distress syndrome has been evaluated in several clinical trials. The results of individual trials do not provide conclusive evidence that administration of a single dose of surfactant improves morbidity or mortality. Meta-analysis is a s…

A meta-analysis of 205 studies involving 23,702 Ss was conducted to determine whether there are sex differences in self-disclosure. Across these studies, women disclosed slightly more than men (d = .18). This effect size was not homogeneous across studies. Several moderator variables were found. Sex of target and the i…

BACKGROUND: Social participation is a core indicator of long-term recovery, but it significantly decreases after a stroke. Diverse single-, bi-, or multi-dimensional interventions showed differing effects on improving stroke survivors' participation. OBJECTIVES: To compare the effectiveness of current interventions ba…

In primary studies, psychotherapy researchers frequently search for mediator and moderator variables that can help them understand the relationship between treatment and outcome. Yet a review of past psychotherapy meta-analyses revealed that none examined the possible role of mediator variables; and although all of the…

For 39 controlled studies on the analgesic effect of antidepressants, a meta-analysis was conducted to get an estimation of the effect size, and to obtain a sight on the possible modes of action and the methodology used. The mean size of the analgesic effect was 0.64. It means that the average chronic pain patient who…

This review aims to identify variables that moderate the outcomes of cognitive-behavior therapy for dysfunctional children. Theoretical considerations led to the hypothesis that children's cognitive developmental level would moderate treatment effectiveness, and analyses confirmed this hypothesis. The effect size (0.92…

Attempts to estimate the effects of dietary cholesterol on serum cholesterol by meta-analysis have not previously included baseline together with added dietary cholesterol in a mathematical model. Mean reported changes in serum cholesterol from 27 studies in which controlled diets were supplied by a metabolic kitchen p…

Recent studies have reported upper gastrointestinal tract bleeding in 5-25% of intensive care unit (ICU) patients with severe stress despite the use of antacids and/or H2-antagonists. To evaluate the efficacy of this regimen, a meta-analysis of all prospective studies on the prevention of stress bleeding, available fro…

The study of testosterone is likely to be prominent in future epidemiological work on endocrine function and the clinical treatment of age-related diseases. Thus, understanding the hormonal changes involved in the normal male aging process will be critical. Using techniques of meta-analysis, the authors examined 88 pub…

A meta-analysis of 51 studies was done to estimate normative mean McGill Pain Questionnaire (MPQ) scores and to assess pain quality and pain intensity as measured by the MPQ in 3,624 subjects with seven painful conditions. Across the painful conditions, all of the estimated normative mean scores were no more than 50% o…