5,043,603 papers found

OBJECTIVE: To overview the methodological quality, report quality and evidence quality of the systematic review (SR) of acupuncture for vascular cognitive impairment ( VCI ). METHODS: The SRs regarding acupuncture for VCI were searched in PubMed, Cochrane Library, EMbase, CNKI, SinoMed, Wanfang and VIP databases. The…

Systematic reviews and meta-analyses (SRMAs) are increasing in popularity, but should they be used to inform clinical decision-making in anaesthesia? We present evidence that the certainty of evidence from SRMAs in anaesthesia (and in general) may be unacceptably low because of risks of bias exaggerating treatment effe…

Evidence-based medicine has become the catch-cry phrase of the 1990s. It is about using evidence from well-designed research and applying it to everyday practice. It would be a difficult task to appraise all the evidence from research without the help of well-prepared systematic reviews. This article examines some aspe…

In this article the authors present a review of previous reviews and meta-analyses, identifying and summarizing the empirical research base on risk and protective factors for future psychosocial problems-specifically externalizing and internalizing problems-among preschool children. The authors also discuss risk and pr…

Mammary sarcomas are uncommon tumors. When tumors like malignant cystosarcomaphyllodes and metaplastic carcinoma, where malignant cartilaginous areas may be present, are excluded, only nine cases have been reported to date.We report another case of primary chondrosarcoma of the breast here. A 24-year-old Mediterranean…

The usage and types of chemicals being developed, with diversified new exposure of workers, are of natural concern to occupational disease. In Korea, with industrialization, application of many chemicals has increased. A large proportion of mortality and disease is due to cancer, and the causal hazardous agents include…

Evidence-based medicine in pediatric neurology is considered an important contributor to the best quality of care. We performed a literature review of all Cochrane reviews from 1996-2010 in pediatric neurology. Some reviews concluded that a certain intervention provided benefits, some concluded that certain interventio…

Systematic reviews and meta-analyses have made a major contribution to the evidence-based management of infections in cancer patients. We review the contribution of systematic reviews with regard to antibiotic, antifungal, antiviral and Pneumocystis pneumonia prophylaxis; antibiotic and antifungal treatment of febrile…

Systematic reviews of acupuncture have tended to support its use, but few applied rigorous inclusion criteria. We tested the credibility of conclusions of systematic reviews of acupuncture published since 1996 by applying rigorous inclusion criteria. Reinterpretation used randomised and double blind trials with valid o…

The author reviewed the placebo-controlled literature on electroconvulsive therapy (ECT) for depression. No study demonstrated a significant difference between real and placebo (sham) ECT at 1 month posttreatment. Many studies failed to find a difference between real and sham ECT even during the period of treatment. Cl…

This review addresses language function and reorganization associated with various forms of epilepsy. Longstanding epilepsy, particularly types with onset early in life, may be associated with changes in the representation of language function in the brain. As a result of this reorganization, language function may be r…

The application of concept mapping software to facilitate the first steps of the research review process is discussed in relation to other software programs currently used for research synthesis. MindMapper software was used to develop a strategy for organizing the results of a comprehensive literature search into disc…

Inconsistent measurement of multimorbidity hinders comparative research and evidence synthesis. To address this, this study is a narrative review, informed by a structured scoping search of three major databases. We synthesized formal expert-consensus studies to identify a foundational core set of conditions that can s…

INTRODUCTION: Cognitive impairment (CI) is common among older hospitalized patients, posing risks for adverse events. However, the extent to which early rehabilitation interventions address CI needs is unclear. This umbrella and scoping review evaluates CI consideration in such interventions during acute hospitalizatio…

There is an increasingly widespread policy momentum to increase patient-centred care and to improve quality of life outcomes within health services. Qualitative research methods are used to elicit in-depth and detailed insights into people's attitudes, beliefs, emotions and experiences-much of which may remain unspoken…

BACKGROUND: There is controversy surrounding the impact of workplace interventions aimed at improving social support and supervisory quality on absenteeism, productivity and financial outcomes. OBJECTIVE: To determine the value of social support interventions for work outcomes. METHODS: Databases were searched for sy…

The Gold Standards Framework aims to optimize primary palliative care for patients nearing the end of their lives. This paper critically reviews the impact of the Gold Standards Framework since its introduction in 2001 and indicates direction for further research and development. Literature was accessed using specific…