Clinical trial of high doses of Bay I 7433 (Copovithane).
Ucci G, Riccardi A, Danova M, +3 more·Drugs under experimental and clinical research
Bay i 7433 (Copovithane) is a biological response modifier with antitumour activity in vivo, but no cytotoxic or cytostatic effect in vitro. A clinical trial of the compound at doses of 15g/m2/week was carried out for six weeks in 10 patients with various forms of cancer. Tolerance was good: no systemic toxicity was ob…