2,645 papers found

OBJECTIVES: Excessive gingival pigmentation can be treated by surgically removing the pigmented gingival tissue with a scalpel, bur, LASER, electrocautery, cryotherapy, chemical peeling, or masking with free gingival grafts. Recently, vitamin C (ascorbic acid), in gel, powder, or liquid has been used alone or as a…

Fibromyalgia (FM) and irritable bowel syndrome (IBS) often occur together. Patients with FM and IBS present similar symptoms, such as pain and fatigue; this leads to a delay in diagnosis and management. This systematic review explored the shared pathophysiology of these conditions in adults, focusing on the r…

BACKGROUND: Misfit at the implant-prosthesis interface arises from small errors that occur during impression-taking, cast fabrication and milling. Implant verification jigs (IVJs) have been described as a quality-control device in fixed implant prosthodontics, yet protocols and indications are inconsistently described…

INTRODUCTION: The radial artery forearm flap (RAFF) is a versatile free tissue transfer used for many clinical presentations. RAFF donor sites typically require a split-thickness skin graft (STSG) for closure. Whilst early rehabilitation of RAFF donor site(s) following STSG commonly involves wrist immobilisation, best…

INTRODUCTION: First aid providers may encounter life-threatening conditions requiring treatment with medications. Given that resuscitation medications in first aid kits may be administered infrequently, first aid providers may face situations where only expired medications are available. OBJECTIVE: This systematic sea…

Obesity is a global health issue characterized by an abnormal or excessive accumulation of body fat, defined as a body mass index (BMI) that exceeds 30 kg/m². Many antiobesity drugs, such as orlistat and quercetin, are often limited by poor solubility and bioavailability. These physicochemical limitations can lead…

INTRODUCTION: Accurate diagnosis of lung metastasis for patients with soft tissue sarcoma (STS) can impact overall survival, but there is considerable variability in imaging utilized to detect metastasis. Chest x-ray (CXR) or computer tomography (CT) scan of the chest are the most common studies in current practice. M…

Postmortem interval (PMI) estimation is a challenge of utmost importance in forensic daily practice. Traditional methods face limitations in accuracy and reliability, particularly for advanced decomposition stages. Recent advances in "omics" sciences, providing a holistic view of postmortem biochemical changes, offer p…

This Umbrella Review aims to gather high-quality evidence on urolithiasis outcomes and complications, comparing extracorporeal shockwave lithotripsy (ESWL), ureteroscopic lithotripsy (URSL), and retrograde intrarenal surgery (RIRS). We incorporated systematic reviews, some containing meta-analyses, into two separate re…

BACKGROUND: This study aimed to evaluate the current status of ophthalmology residency training in Switzerland and provide insights for enhancing training programs. MATERIALS AND METHODS: The survey covered demographic data such as gender, age, workplace, and year of residency, as well as working conditions, current p…

: Liquid biopsy is a method that could potentially improve the management of thyroid cancer (TC) by enabling the detection of circulating tumor DNA and RNA (ctDNA, ctRNA). Themutation appears to be the most representative example of a biomarker in liquid biopsy, as it is the most specific mutation for TC and a target f…

PURPOSE: Neurosurgery training in the UK has undergone significant changes over the past few years, including the new competency-based curriculum and a reduction of elective operating due to the pandemic. We conducted a comprehensive survey to assess UK neurosurgical trainees' experiences and perceptions to develop tar…

BACKGROUND: Free open access medical education (FOAM) resources have become increasingly popular in graduate medical education. Despite their accessibility, the assessment of FOAM resources' quality is challenging due to their decentralized nature and the diverse qualifications of their authors and distribution platfor…

Polycystic ovary syndrome (PCOS) is one of the most pressing problems in endocrine gynecology. The main signs of the disease are hyperandrogenism, menstrual and/or ovulatory dysfunction, and polycystic ovarian structure according to ultrasound. Women with PCOS are at risk for developing metabolic syndrome, type 2 diabe…

BACKGROUND: Locum doctors give practices flexibility to deliver patient services but there are concerns about the impact of locum working on continuity of care, patient safety, team function, and cost. AIM: To explore locum working in English general practices, and understand why and where locum doctors were needed an…

OBJECTIVES: The objectives of this review are to (1) analyze the core concepts of emotional intelligence self-perception, self-expression, interpersonal relationships, decision-making skills, and stress management and their role in professional identity formation, and (2) investigate the methods and strategies to incor…

INTRODUCTION: In recent years, eye-tracking has been proposed as a promising tool to identify potential biomarkers for mental disorders, including major depression. We will conduct an updated systematic review and meta-analysis on eye-tracking research in adults with major depressive disorder or other clinically diagno…

Collective meal contexts such as restaurants, cafeterias and canteens can help accelerate transitions to healthier and more sustainable diets. However, evidence from intervention studies on these contexts lacks integration. This scoping review aimed to map determinants of dietary change in collective meal contexts acro…

OBJECTIVES: To describe the current state of the art regarding technological advances in full-automatic tooth segmentation approaches from 3D cone-beam computed tomography (CBCT) images. MATERIALS AND METHODS: In March 2023, a search strategy without a timeline setting was carried out through a combination of MeSH ter…

INTRODUCTION: The electronic collection of patient data is used for a large variety of conditions. The boundaries of its use in initial diagnostics and the extent to which it can replace specialist contact, however, remain vague. Our newly developed virtual diagnostic process for common sleep disorders involves digital…