Endocrine effects of valproic acid therapy in girls with epilepsy: a prospective study.
Goldberg-Stern Hadassa, Yaacobi Eyal, Phillip Moshe, +1 more·European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
BACKGROUND/AIM: It is controversial whether the endocrine dysfunction in epilepsy patients is caused by the epilepsy itself, the antiepileptic therapy, or both. We prospectively evaluated the long-term impact of valproic acid monotherapy compared to other anti-epileptic drugs on anthropometric, metabolic, hormonal, and…