11,607,948 papers found

Biomarkers are measured repeatedly in clinical studies until a pre-defined endpoint, such as death from certain causes, is reached. Such repeated measurements may present a dynamic process for understanding when to expect the study's endpoint. Joint modelling is often employed to handle such a model. Typically, shared…

A retrospective cohort study was performed in five Italian obstetrical centres from 1984 to 1991 in order to verify the association between chorionic villus sampling (CVS) and transverse limb reduction defects (TLRDs). TLRD rates by period of gestation at CVS were calculated, and the study's results were compared with…

Stromal cell-derived factor 1 (SDF-1) is known to influence bone marrow stromal cell (BMSC) migration, osteogenic differentiation, and fracture healing. We hypothesize that SDF-1 mediates some of its effects on BMSCs through epigenetic regulation, specifically via microRNAs (miRNAs). MiRNAs are small non-coding RNAs th…

Much biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study's generalisability. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Initiative developed recommendations on what sh…

This article draws on data from a research project that combined participant observation with in-depth interviews to explore family relationships and experiences of everyday life during life-threatening illness. In it I suggest that death has often been theorised in ways that make its 'mundane' practices less discernib…

OBJECTIVE: This study's purpose was to assess knowledge and concerns related to the human papillomavirus (HPV) vaccine among underserved Latina women and Latina mothers of female adolescents and to explore differences between those in the vaccinated and those in the unvaccinated groups. MATERIALS AND METHODS: We condu…

BACKGROUND: Enzyme-assisted subcutaneous infusion (EASI), with subcutaneous human recombinant hyaluronidase pretreatment, may offer an alternative to standard intravenous (IV) access. OBJECTIVES: This study's objectives were to assess paramedic (Emergency Medical Technician-Paramedic [EMTP])-placed EASI access in volu…

The grip force applied to a cylindrical handle is a function of the measurement reference axis. So far, however, no attempt has been made to fully describe the exact form of this function. The objectives of this study were to examine some fundamental characteristics of grip forces and to explore the basic pattern of th…

The methods section of a research paper provides the information by which a study's validity is judged. Therefore, it requires a clear and precise description of how an experiment was done, and the rationale for why specific experimental procedures were chosen. The methods section should describe what was done to answe…

The impact of turnover is a major concern for the chief nurse executive. This study provides nurse administrators with information necessary to more fully understand the impact of turnover and assists them in developing and defending retention strategies. Part 1 addresses the conceptual model used to guide the study; P…

Our study concerns 20 patients affected by "Sick Sinus Syndrome", these has been observed in our Coronary Care Unit during the period 1-7-1976 to 26-4-1979. All patients has been submitted to an electrophysiological study of the conduction system; of those only 16 has been treated with a permanent PMK, the other 4 with…

During the 1980s Motivational Interviewing emerged as one of the memes of the addictions field. This occurred despite the lack of scientific evidence supporting its utility. In this paper findings of a controlled trial of a brief motivational intervention with illicit drug users (n = 122) attending a methadone clinic a…

Previous studies have established that there is a relationship between efficacy beliefs and procrastination. Theory and research on motivation suggest that visual imagery (the capacity to create vivid mental images) may be implicated in this relationship and in the general tendency to procrastinate. This study's aim wa…

Background and purpose - The incidence of knee replacements (KRs) has increased in the past decades. Previous studies have forecast a continuous and almost exponential rise in the use of KRs, but this rise must cease at some point. We estimated when and at what incidence the use of KRs will plateau in Denmark.Patients…

Individual studies in patient-oriented research, whether described as "comparative effectiveness" or using other terms, are based on underlying methodological designs. A simple taxonomy of study designs includes randomized controlled trials on the one hand, and observational studies (such as case series, cohort studies…

Leadership style is crucial for developing organizational culture, achieving goals, and shaping relationships. The site coordinator of clinical education (SCCE) is an important leader for effective physical therapy clinical education, yet few studies examine the role. This study's purposes were to discern the SCCEs' se…

This article studies the impact of intervention measures with nudge characteristics on residents' waste separation behaviours under the background of new 'Beijing Municipal Regulation on Domestic Waste Management'. We analyse whether and how nudge interventions affect residents' waste separation behaviours through the…

The study's objective was to ascertain the general public's attitudes regarding the covid-19 vaccine in Pakistan. A cross sectional design and e-survey was conducted by 1647 general public. The sample was divided into two sections: urban (702) and rural (945). The majority of participants were between the ages of 18 an…

Electrovestibulography (EVestG) recordings have been previously applied toward classifying and/or measuring the severity of several neurological disorders including depression with and without anxiety. This study's objectives were to: (1) extract EVestG features representing physiological differences of healthy women d…

Low health literacy (HL) has been associated with several negative health outcomes, yet routine HL screening is not commonplace. This study's purpose was to determine the feasibility of incorporating HL screening into the electronic health record (EHR) of patients admitted to a large Mid-Atlantic teaching hospital. Aft…