381,523 papers found

OBJECTIVE: To determine whether low protein diets retard the development of end stage renal disease. DESIGN: Meta-analysis of 46 trials since 1975, from which six randomised controlled trials were selected. SETTING: Five trials in Europe and one in Australia between 1982 and 1991. SUBJECTS: 890 patients with mild to…

OBJECTIVES: To compare the effectiveness of various endotracheal tube (ETT) cuff materials, shapes, and antimicrobial coatings in preventing ventilator-associated pneumonia (VAP) through a network meta-analysis. METHODS: Six databases were searched up to February 2025 for relevant randomized controlled trials (RCTs).…

A recent meta-analysis published in Parasites & Vectors [17(1):444, 2024] re-evaluated the prevalence of feline hemotropic Mycoplasma spp. in Ctenocephalides felis. The authors compared prevalence studies using different PCR primers: those employing Jensen or Manvell primers reported high prevalence (~ 33%), whi…

Developmental change in twin similarity was examined with age contrasts in a meta-analysis of twin studies from 1967 through 1985. Intraclass rs were coded from 103 papers that included data for monozygotic or dizygotic twins, or for both, on personality or intelligence variables. Analyses indicated that there was a ge…

The study compares the health impacts of various nonpharmacologic interventions on cognitive function, daily functioning, depression, and quality of life among people living with dementia.A comprehensive search was conducted across three databases-PubMed, Airiti Library, and Scopus-to identify eligible randomized contr…

Replacement therapy with surfactant extracts in premature infants with respiratory distress syndrome has been evaluated in several clinical trials. The results of individual trials do not provide conclusive evidence that administration of a single dose of surfactant improves morbidity or mortality. Meta-analysis is a s…

Attempts to estimate the effects of dietary cholesterol on serum cholesterol by meta-analysis have not previously included baseline together with added dietary cholesterol in a mathematical model. Mean reported changes in serum cholesterol from 27 studies in which controlled diets were supplied by a metabolic kitchen p…

A meta-analysis of 51 studies was done to estimate normative mean McGill Pain Questionnaire (MPQ) scores and to assess pain quality and pain intensity as measured by the MPQ in 3,624 subjects with seven painful conditions. Across the painful conditions, all of the estimated normative mean scores were no more than 50% o…

INTRODUCTION: Different image-enhanced endoscopy (IEE) methods have shown promise in improving colorectal lesion detection, but direct comparisons remain limited. This network meta-analysis compared the detection and diagnostic performance of various IEE modalities for colorectal lesions. METHODS: We searched PubMed,…

Four randomized clinical trials comparing cyclophosphamide plus cisplatin (CP) versus cyclophosphamide, doxorubicin, and cisplatin (CAP) individually failed to show a significant survival difference in the treatment of ovarian carcinoma. However, by pooling 1,194 patients from these trials in a meta-analysis, there is…

BACKGROUND AND OBJECTIVES: Chronic subdural hematoma (cSDH) is a common neurosurgical condition, particularly in elderly patients. Middle meningeal artery embolization (MMAE) has emerged as a promising intervention, while statins have been explored for their anti-inflammatory and angiogenesis-modulating properties. Thi…

Studies designed to examine effects of weight reduction by dieting on total cholesterol (TC), low-density-lipoprotein cholesterol (LDL-C), high-density-lipoprotein cholesterol (HDL-C), very-low-density-lipoprotein cholesterol (VLDL-C), and triglycerides (TGs) have reported inconsistent results. The purpose of this stud…

Whether ceftazidime monotherapy is equal in efficacy to combination regimens (Comb) for empiric treatment of febrile neutropenic patients was tested using meta-analysis. Published studies and abstracts of ceftazidime trials were identified, their quality assessed, the efficacy data abstracted and pooled, and effects of…

The role of thermography for diagnosing lumbar radiculopathy was evaluated by literature review and meta-analysis. From 81 relevant citations, 28 studies could be analyzed for diagnostic-accuracy data (sensitivity and specificity) and method. Diagnostic-accuracy data varied significantly between studies; therefore mean…

BACKGROUND: Tic disorder (TD) is a neuropsychiatric disorder that often begins in childhood or adolescence. Acupuncture and moxibustion are alternative therapies that have been demonstrated to be effective in the treatment of TD. Over the past few decades, several systematic reviews (SRs) and meta-analyses have reporte…

A meta-analysis was performed to examine the relation of patients' sociodemographic characteristics to their satisfaction with medical care. The sociodemographic characteristics were age, ethnicity, sex, socioeconomic status (three indices), marital status, and family size. Greater satisfaction was significantly associ…

This review aims to identify variables that moderate the outcomes of cognitive-behavior therapy for dysfunctional children. Theoretical considerations led to the hypothesis that children's cognitive developmental level would moderate treatment effectiveness, and analyses confirmed this hypothesis. The effect size (0.92…

A meta-analysis of studies examining the interrater reliability of the standard practice of peer assessments of quality of care was conducted. Using the Medline, Health Planning and Administration, and SCISEARCH databases, the English-language literature from 1966 through 1991 was searched for studies of chance correct…