386,758 papers found

OBJECTIVE: To evaluate the risk of major injuries associated with Veress, open (Hasson), direct and optical abdominal entry methods in laparoscopy. METHODS: Network meta-analysis was performed using penalized logistic regression. Pairwise meta-analysis was carried-out using Bayesian binomial-normal hierarchical models…

The study compares the health impacts of various nonpharmacologic interventions on cognitive function, daily functioning, depression, and quality of life among people living with dementia.A comprehensive search was conducted across three databases-PubMed, Airiti Library, and Scopus-to identify eligible randomized contr…

Four randomized clinical trials comparing cyclophosphamide plus cisplatin (CP) versus cyclophosphamide, doxorubicin, and cisplatin (CAP) individually failed to show a significant survival difference in the treatment of ovarian carcinoma. However, by pooling 1,194 patients from these trials in a meta-analysis, there is…

BACKGROUND: Projections for major health outcomes are crucial for decision-making to enable early interventions. Pooling results from meta-analyses with estimates based on individual participant data can reduce uncertainty and improve generalizability. However, current methods for meta-meta-analyses of nonlinear functi…

Meta-analysis of evaluation studies of rape education programs aimed at college students examined which program characteristics were related to participants' rape-supportive attitude change. Linear regression analyses revealed that: (a) published studies yielded greater attitude change than dissertations, presentations…

Replacement therapy with surfactant extracts in premature infants with respiratory distress syndrome has been evaluated in several clinical trials. The results of individual trials do not provide conclusive evidence that administration of a single dose of surfactant improves morbidity or mortality. Meta-analysis is a s…

In primary studies, psychotherapy researchers frequently search for mediator and moderator variables that can help them understand the relationship between treatment and outcome. Yet a review of past psychotherapy meta-analyses revealed that none examined the possible role of mediator variables; and although all of the…

A meta-analysis of 205 studies involving 23,702 Ss was conducted to determine whether there are sex differences in self-disclosure. Across these studies, women disclosed slightly more than men (d = .18). This effect size was not homogeneous across studies. Several moderator variables were found. Sex of target and the i…

For 39 controlled studies on the analgesic effect of antidepressants, a meta-analysis was conducted to get an estimation of the effect size, and to obtain a sight on the possible modes of action and the methodology used. The mean size of the analgesic effect was 0.64. It means that the average chronic pain patient who…

BACKGROUND AND OBJECTIVES: Chronic subdural hematoma (cSDH) is a common neurosurgical condition, particularly in elderly patients. Middle meningeal artery embolization (MMAE) has emerged as a promising intervention, while statins have been explored for their anti-inflammatory and angiogenesis-modulating properties. Thi…

Recent studies have reported upper gastrointestinal tract bleeding in 5-25% of intensive care unit (ICU) patients with severe stress despite the use of antacids and/or H2-antagonists. To evaluate the efficacy of this regimen, a meta-analysis of all prospective studies on the prevention of stress bleeding, available fro…

A meta-analysis of studies examining the interrater reliability of the standard practice of peer assessments of quality of care was conducted. Using the Medline, Health Planning and Administration, and SCISEARCH databases, the English-language literature from 1966 through 1991 was searched for studies of chance correct…

OBJECTIVE: To determine whether low protein diets retard the development of end stage renal disease. DESIGN: Meta-analysis of 46 trials since 1975, from which six randomised controlled trials were selected. SETTING: Five trials in Europe and one in Australia between 1982 and 1991. SUBJECTS: 890 patients with mild to…

This meta-analysis evaluates outcomes in patients undergoing bioprosthetic aortic valve replacement (bAVR), comparing different antithrombotic strategies. We conducted a systematic search through May 2024. A standard meta-analysis compared outcomes between patients who received anticoagulation therapy (AC) and those wh…

BACKGROUND: This study aimed to synthesize evidence on the relative effectiveness of antimalarial drugs used as chemoprevention of malaria in pregnancy (MIP) using network meta-analysis (NMA). METHODS: Searches for eligible studies were made in multiple electronic databases, including PubMed. Randomized controlled tri…

The study of testosterone is likely to be prominent in future epidemiological work on endocrine function and the clinical treatment of age-related diseases. Thus, understanding the hormonal changes involved in the normal male aging process will be critical. Using techniques of meta-analysis, the authors examined 88 pub…

Developmental change in twin similarity was examined with age contrasts in a meta-analysis of twin studies from 1967 through 1985. Intraclass rs were coded from 103 papers that included data for monozygotic or dizygotic twins, or for both, on personality or intelligence variables. Analyses indicated that there was a ge…

BACKGROUND: Community-based rehabilitation is critical for functional recovery in older adults after hip fracture, yet the optimal strategy remains uncertain. Previous reviews are limited by the pooling of heterogeneous interventions and an incomplete assessment of evidence quality. This network meta-analysis (NMA) aim…

This review aims to identify variables that moderate the outcomes of cognitive-behavior therapy for dysfunctional children. Theoretical considerations led to the hypothesis that children's cognitive developmental level would moderate treatment effectiveness, and analyses confirmed this hypothesis. The effect size (0.92…