5,082,726 papers found

Systematic reviews are accepted as a robust and less biased means of appraising and synthesizing results from high-quality studies. This report collated and summarized all the systematic review evidence relating to the diagnosis and management of trauma-related coagulopathy and transfusion, thereby covering the widest…

OBJECTIVE: validated imaging outcome tools to assess response to therapies in a single joint are required. Our aim was to review the published literature to ascertain the responsiveness of novel imaging techniques as outcome measures in interventional therapeutic studies of knee arthritis. METHODS: an Ovid Medline sea…

BACKGROUND: To identify associations between polyphenol intake and health and disease outcomes in cohort studies, it is important to identify biomarkers of intake for the various compounds commonly consumed as part of the diet. OBJECTIVE: The objective of this systematic review was to assess the usefulness of polyphen…

AIMS AND OBJECTIVES: The objective of this study was to identify and to assess the quality of evidence-based guidelines and systematic reviews we used in the case of oral mucositis, to apply general quality criteria for the prevention and treatment of oral mucositis in patients receiving chemotherapy, radiotherapy or b…

The goals of this systematic review and meta-analysis were to ascertain whether studies of nonsteroidal anti-inflammatory drugs (NSAIDs) summarized in the FDA reviews are ultimately published, to compare the methodologic and population characteristics of studies summarized in the FDA reviews with those reported in peer…

PURPOSE: To systematically review the methodology and use of neuropsychological tests in randomized controlled trials (RCTs) of antiepileptic drugs (AEDs) in patients with epilepsy. METHODS: Trial reports were found by searching Medline 1966-1996 and searching through journals by hand. Inclusion and exclusion criteria…

STATEMENT OF PROBLEM: Osseodensification has been proposed as a bone preserving osteotomy technique to improve implant primary stability compared with conventional drilling; however, evidence from existing systematic reviews remains inconsistent. PURPOSE: The purpose of this umbrella review was to synthesize and criti…

Dysfunctional behavior in active military personnel is a complex and challenging issue for military forces worldwide. Effective management of this issue requires a comprehensive understanding of the factors that contribute to dysfunctional behavior in military populations. The current study presents an umbrella review…

PURPOSE: Anxiety and pain are two of the most prevalent clinical problems seen in the perioperative period. Music intervention has been shown to decrease anxiety and pain levels in patients undergoing surgery. This umbrella review aimed to summarize current evidence regarding music listening and its effects on patient…

BACKGROUND: Limited resources imply the need for prioritization; this also applies to the conduct of Cochrane Reviews. Therefore, processes for identifying the most important topics for review should be determined. AIM: The aim of this study was to describe some examples of prioritization approaches used within Cochra…

AIM: Since 2007 we focused our attention as EJPRM to the best available clinical evidence as offered by the Cochrane Collaboration. Due to the absence of a specific Rehabilitation Group (only a Field exists), reviews of PRM interest are in different groups and not easy to find. Consequently, the EJPRM offer the service…

BACKGROUND: Scoliosis is a common finding in children with Chiari I malformation and syringomyelia. The development of scoliosis associated with a Chiari malformation typically has been ascribed to the presence of syringomyelia. Decompression of the hindbrain hernia will often alleviate the syringomyelia and, in many c…

To improve assessment and management of pain in nonverbal older adults with dementia, an effective means of recognizing and evaluating pain in this vulnerable population is needed. The purpose of this review is to critically evaluate the existing tools used for pain assessment in this population to provide recommendati…

UNLABELLED: Seven new anti-epileptic drugs (AEDs) have become available in Ireland over the last 10 years; data from animal models and clinical trials suggest that they have a superior safety profile to older AEDs. A specific relationship between epilepsy and psychiatric co-morbidity has long been recognised, including…

BACKGROUND: Although the efficacy of interval training for improving body composition has been summarized in an increasing number of systematic reviews in recent years, discrepancies in review findings and conclusions have been observed. OBJECTIVE: This study aims to synthesize the available evidence on the efficacy o…

Opioids contribute to more than 60 000 deaths annually in North America. While the expansion of overdose education and naloxone distribution (OEND) programs has been recommended in response to the opioid crisis, their effectiveness remains unclear.To conduct an umbrella review of systematic reviews to provide a…

Well-conducted systematic reviews and meta-analyses provide the best quality evidence for clinical decision-making. This article presents the key role of systematic reviews in clinical decision-making, discussing the steps and pitfalls to avoid in conducting systematic reviews and meta-analyses.

PURPOSE: To synthesize evidence on platelet-rich fibrin (PRF) and its derivatives for postoperative outcomes after mandibular third molar extraction, and to re-evaluate the methodological quality of available systematic reviews against the prior umbrella review (Yang 2024). METHODS: PubMed, Cochrane CDSR, and Epistemo…

AIMS: Community treatment orders have been introduced in many jurisdictions with increasing use over time. We conducted a rapid umbrella review to synthesise the quantitative and qualitative evidence from systematic reviews and/or meta-analyses of their potential harms and benefits. METHODS: A systematic search of Med…

AIM: To provide a comprehensive literature review on the perceived correlation between COVID-19 vaccination and corneal allograft rejection, and to characterize risk factors, time course, graft outcomes and proposed immunological basis. METHODS: A literature review was conducted in August 2023 using 4 electronic datab…