2,589 papers found

Negative healthcare professional experiences of work can undermine health system stability by contributing to shortages, burnout and poor retention. Research into doctors' and nurses' working conditions indicates the important role of 'solidarity' to their working experience. There is limited understanding of formal (t…

BACKGROUND: Osgood-Schlatter disease (OSD) is a non-traumatic knee problem that is primarily observed in sports-active children and adolescents aged 8-15 years. AIM: To determine the incidence of OSD and to gain an insight into the management of children and adolescents with OSD in general practice. DESIGN AND SETTIN…

BACKGROUND: Since scaling and root planing are not always successful, predominantly when access to periodontal defects is compromised, various antimicrobial agents as adjuncts have been suggested to enhance their efficacy. Gel vehicles delivering chlorhexidine (CHX) have become available and tested for these indication…

BACKGROUND: Acute Lymphoblastic Leukemia (ALL) is the most common pediatric cancer, with significant advancements in treatment leading to over 90% five-year event-free survival rates in developed countries. However, disruptions in health behaviors during treatment, such as diet, activity, and sleep, can negatively impa…

INTRODUCTION: Women who live in humanitarian settings are three times more likely to die than those who live in peaceful environments. Person-centred maternity care (PCMC) is a fundamental human right for every woman, yet it is often overlooked in humanitarian contexts. This scoping review aims to summarise person-cent…

OBJECTIVE: We aim to describe the current programmatic structure and learning environment of US neonatal-perinatal medicine (NPM) fellowship programs. STUDY DESIGN: All U.S. NPM program directors (PDs) and associate program directors (APDs) were surveyed. Descriptive statistics for quantitative questions and thematic…

As pediatric palliative care (PPC) expands within institutions and nationally, little guidance is available on building outpatient programs.We asked outpatient PPC (OPPC) program leaders in the United States about clinic development experiences to gather advice for growing programs.As part of a larger OPPC study, 48 fr…

BACKGROUND: Diabetes mellitus is a complex metabolic disorder that has an enormous impact on people's quality of life and health. Although there is no doubt about the effectiveness of oral hypoglycemic agents combined with lifestyle management in controlling diabetes, no individual has ever been reported to have been c…

Human immunodeficiency virus (HIV) is a viral infection which progressively leads to acquired immunodeficiency syndrome (AIDS) in the absence of treatment. This happens through the destruction of crucial cells in the immune system, such as the helper T cells, dendritic cells, and macrophages. Since the first case…

INTRODUCTION: Inadequate management of pain and sedation in critically ill children can cause unnecessary suffering and agitation, but also delirium and iatrogenic withdrawal. It is, therefore, important to address these four interrelated conditions together. Some clinical practice guidelines (CPGs) are available for t…

BACKGROUND: Bimekizumab is a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL-17A. OBJECTIVES: To assess patients' ability to self-inject bimekizumab subcutaneously using a 1 mL safety syringe or auto-injector. METHODS: DV0002 and DV0006 were sub-studies of BE BRIGHT, a multic…

BACKGROUND: laparoscopic surgery is mainly performed in general anesthesia. Symptomatic patients infected with COVID-19 needing surgery are however at higher risk for COVID-19 complications in general anesthesia than in regional anesthesia. Even so, Covid transfection is a hazard to medical personnel during the intubat…

Time restricted feeding (TRF) as a form of intermittent fasting (IF) has gained popularity because its ability to reduce body mass (BM) without an emphasis on caloric restriction. However, how this dietary protocol may affect health, fitness, and performance in a relatively healthy cohort remains less clear. The purpos…

BACKGROUND: Anti-interleukin (IL)-17 biologic agents used to treat psoriasis are associated with onset/exacerbation of inflammatory bowel disease (IBD). OBJECTIVES: To determine the incidence of IBD or serious gastrointestinal-related adverse events (GI SAEs) in patients with moderate-to-severe psoriasis treated with…

: Due to the COVID-19 pandemic and the strict national policies regarding social distancing behavior in Europe, America and Australia, people became reliant on social media as a means for gathering information and as a tool for staying connected to family, friends and work. This is the first trans-national study explor…

BACKGROUND: Colorectal cancer (CRC) is a major cause of cancer deaths worldwide. Accumulating evidence suggests a potentially important role of colorectal infection with Fusobacterium nucleatum (F. nucleatum) in colorectal carcinogenesis. We conducted a systematic review, including both a qualitative synthesis and a me…

INTRODUCTION: Transient acantholytic dermatosis has been frequently reported in patients with malignancies. While paraneoplastic cases have rarely been reported, most eruptions occur in the setting of chemotherapeutic agents. Management is based on limited data and primarily with topical steroids and topical emollients…

BACKGROUND: Stereotactic radiosurgery (SRS) for benign intracranial meningiomas is an established treatment. OBJECTIVE: To summarize the literature and provide evidence-based practice guidelines on behalf of the International Stereotactic Radiosurgery Society (ISRS). METHODS: Articles in English specific to SRS for b…

BACKGROUND AND PURPOSE: Qualitative studies about the abnormalities appreciated on routine magnetic resonance imaging (MRI) sequences in prematurely born adults are lacking. This article aimed at filling this knowledge gap by (1) qualitatively describing routine imaging findings in prematurely born adults, (2)&#xa…

BACKGROUND: The UK has experienced significant immigration from Eastern Europe following European Union (EU) expansion in 2004, which raises the importance of equity and equality for the recent immigrants. Previous research on ethnic health inequalities focused on established minority ethnic groups, whereas Eastern Eur…