44,688 papers found

Gastrointestinal (GI) diseases are manifestations of abnormal brain-gut interactions, which are closely related to brain functions. Systematic sorting of the central mechanisms related to GI functions is of great clinical significance for preventing and treating GI disorders. We therefore conducted a literature search…

BACKGROUND: The central retinal artery (CRA) has been described as one of the first branches of the ophthalmic artery.It arises medial to the ciliary ganglion and after a sinuous path within the orbital cavity it penetrates the lower surface of the dura mater that covers the optic nerve, approximately 1 cm behind the e…

: Interest in the symptoms pertaining to Costen's syndrome has revived in recent years. The aim of this work is to address the symptoms of Costen's syndrome from the basic science perspective: A minireview of the literature related to Costen's syndrome symptoms was performed by retrieving relevant articles from the Pub…

INTRODUCTION: Paraoxonase-1 (PON1) is a Ca(2+) dependent, high-density lipoprotein-associated lactonase which is capable of retarding/inhibiting low-density lipoprotein (LDL) oxidation. LDL oxidation is believed to be central to the initiation and progression of atherosclerosis, therefore, PON1 is considered to be athe…

The Spring 2015 issue of the International Journal of Telerehabilitation (IJT) contains original research that analyzes provider perspectives on the use of telepractice to serve the families of children who are deaf or hard of hearing. Two case studies examine the utility of administering Facial Affect Training through…

BACKGROUND: Thyroid cancer in pediatric patients is distinct from adult-onset thyroid cancer due to differences in disease presentation, management and outcomes. This meta-analysis delves into contemporary data on managing pediatric differentiated thyroid cancer (DTC), assessing outcomes, such as recurrence and mortali…

BACKGROUND: Central nervous system (CNS) infections carry a severe prognosis and often require intensive care unit (ICU) admission. This study evaluated the prognostic value of neuroimaging in patients with all-type CNS infections. METHODS: Using a predefined strategy, we first conducted a systematic search of PubMed/…

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that leads to nerve atrophy. Ultrasonography has a significant role in the diagnosis of ALS. AIM: We aimed to sonographically assess the size of all peripheral nerves and cervical nerve roots in ALS compared to controls. METHODS: We search…

BACKGROUND: Thymic carcinoma is a rare tumor arising from the epithelial thymic tissue, yet among mediastinal tumors, it is the most common malignant entity. Thymic carcinoma often causes no symptoms and is incidentally discovered. Adjuvant radiotherapy is recommended, particularly in cases of incomplete resection and…

Acute bronchiolitis caused by the respiratory syncytial virus triggers an inflammatory response with the production and release of several pro-inflammatory cytokines. Evidence suggests that their levels are associated with the severity of the infection. This systematic review and meta-analysis aim to assess whether the…

The objective of this systematic review was to assess the analgesic efficacy of duloxetine (DLX) for fibromyalgia (FM) and find out which dosage between 60 mg/d DLX and 120 mg/d DLX was more suitable for clinical application.A systematic search through multiple databases (Cochrane Central Register of Cont…

BACKGROUND: Conventional complete dentures and implant supported overdentures are commonly used by dentists to treat completely edentulous mandibular arches. There have been problems associated with retention and stability while treating completely edentulous mandibular arches compared to maxillary arches. Many factors…

This systematic review aimed to evaluate the efficacy and safety of preemptive analgesia using oral steroidal and nonsteroidal anti-inflammatory drugs (NSAIDs) in adults undergoing dental implant surgery. A comprehensive search was conducted in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (via…

BACKGROUND: Anemia is a prevalent complication in neurocritical patients and contributes to secondary brain damage by diminishing the oxygen supply to the brain. Although red blood cell transfusions may enhance cerebral oxygen delivery, whether this intervention improves patient outcomes remains unclear. METHODS: We s…

BACKGROUND: Agitation is a common reason for psychiatric consultation in the general hospital. The consultation-liaison (CL) psychiatrist is often tasked with teaching the medical team how to manage agitation. OBJECTIVE: The purpose of this scoping review is to explore what resources the CL psychiatrist has for educat…

PURPOSE: Accumulating research suggests that psychotherapy helps improve abstinence but the difference in the efficacy of multiple psychotherapies in alcohol use disorder (AUD) remains to be explored. PATIENTS AND METHODS: A systematic search of databases (Pubmed, Embase, Cochrane Central Register of Controlled Trials…

INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) is a common comorbidity of type 2 diabetes mellitus (T2DM), and no approved therapies are currently available. A meta-analysis was performed to investigate the effects of liraglutide on NAFLD in patients with T2DM. METHODS: Medline (via PubMed), Embase (via Elsevi…

BACKGROUND: Coronavirus disease 2019 (COVID-19) is an infection with possible serious consequences. The plasma of recovered patients might serve as treatment, which we aim to assess in the form of a prospective meta-analysis focusing on mortality, multi-organ failure, duration of intensive care unit stay, and adverse e…

BACKGROUND: Malaria is one of the major contributing risk factors for poor development of children living in low- and middle-income countries (LMICs). However, little is known about the specific domains of cognition and behavior that are impacted by malaria, the extent of these deficits, and the different types of the…

BACKGROUND: Oscillating-rotating power toothbrushes have been proven clinically efficacious. To our knowledge, a comprehensive review of all clinical and laboratory investigations solely comparing the safety of these toothbrushes to the standard of care (i.e., manual toothbrushes) has not been published. The aim of thi…