42,305 papers found

OBJECTIVE: Hyperexcitability of the central nervous system plays an important role in the development and maintenance of chronic pain in adults. This knowledge has led to improved treatment strategies within this population. In children, however, research on the presence of central hyperexcitability is scarce. To furth…

OBJECTIVE: The objective of this review was to determine the effect of educational programs that have been implemented in acute health care settings to manage or prevent aggressive behaviors toward staff perpetrated by patients, families, or visitors. INTRODUCTION: Health care staff working within acute-level and tert…

BACKGROUND: is a common cause of human respiratory infections. Extrapulmonary manifestations include diseases of the central nervous system (CNS). METHODS: To summarize the current knowledge on-associated CNS complications, cases published in PubMed between 2015 and 2025 were reviewed. RESULTS: We included 70 studies…

BACKGROUND: Retinal degeneration and neuroinflammation are often early hallmarks of different subtypes of neuronal ceroid lipofuscinosis (NCL) in patients and genetic animal models. OBJECTIVE: This article gives a summary of recently published research articles and novel concepts in the field of NCL-related neuroinfla…

BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. The exact pathogenesis behind the development of MS is unknown. This study aims to elucidate the role of fibrinogen in MS pathology and discuss candidacy as a biomarker for disease management. METHOD: The…

BACKGROUND: The cerebellum plays a central role in the online, real-time control, and long-term modulation of eye movements. EVIDENCE ACQUISITION: We reviewed the latest (fifth) edition of Leigh and Zee's textbook, The Neurology of Eye Movements, and literature in PUBMED using the following terms: cerebellum, flocculu…

BACKGROUND: The spinal meninges have received less attention than the cranial meninges in the literature, although several points remain debatable and poorly understood, like their phylogenesis, their development, and their interactions with the spinal cord. Their constancy among the chordates shows their crucial impor…

CONTEXT: Warburgia (Canellaceae) species have a long history of ethnomedicinal uses in east, central and southern Africa. Due to the popularity of Warburgia as a source of ethnomedicines; all the species are severely over-harvested throughout their distributional ranges. OBJECTIVE: This review documents fragmented inf…

The Sixth meeting of the International Society for the Prevention of Tobacco Induced Diseases (ISPTiD) was held in Little Rock, Arkansas on November 2-4, 2007 and has brought together 140 participants, scientists and experts in this specialized field from 30 countries across the World. The central theme of the conferen…

This report discusses the issues involved in the diagnosis and management of tetanus. A 29-year-old female with a history of illicit drug use presented with progressive tetany secondary to an abscess on her forearm from subcutaneous injections. She was managed in the intensive care unit for 29 days and was discharged t…

Odontogenic fibroma (OF) is a rare benign odontogenic tumor deriving from the dental mesenchymal tissue and accounting for less than 5% of all odontogenic tumors. This paper presents an aggressive histologically diagnosed central odontogenic fibroma (COF) in a 17-year-old girl characterized by asymptomatic rapid growth…

BACKGROUND: The supposed lack of a hemodynamic impact of peritoneal dialysis (PD) has been challenged recently in different studies, although the observed effects are still far below those seen on hemodialysis (HD), and the underlying mechanisms are unclear. METHODS: Literature overview based on Pubmed search with key…

INTRODUCTION: Patients with fibromyalgia (FM) have innumerable complaints due to the central amplification of somatic stimuli. The aim of this paper was to review the ear complaints in patients with FM. METHODS: A review of articles published in PubMed/MEDLINE, Embase, Web of Science, and Scopus from 1966 to June 2023…

Human helminth zoonosis is one of the most encountered helminthiases worldwide. Representative diseases includeand, which are common nematodes prevalent in dogs and cats. The infiltration of these roundworms in the human body through contaminated food or nematode eggs could lead to central nervous system injury as the…

Acute Venous Thromboembolism (VTE) is a common disease associated with the significant morbidity and mortality. We reviewed clinical outcomes systematically with Dabigatran as a direct oral anticoagulants (DOAC) for treatment of acute VTE. We used Ovide, PubMed, Cochrane (CENTRAL), EMBASE, Scopus, Science Direct, LILAC…

Supratentorial endodermal cysts are very rare pathological entities. Their pathoembryology is largely unknown and they can represent a diagnostic challenge. A research performed on the PubMed database in December 2010, to screen for supratentorial endodermal cyst studies, demonstrated that since 1960 only 31 supratento…

It is thought that the prefrontal cortex (PFC) subserves cognitive control processes by coordinating the flow of information in the cerebral cortex. In the network of cortical areas the central position of the PFC makes difficult to dissociate processing and the cognitive function mapped to this region, especially when…

OBJECTIVES: To review the literature on how implant surface characteristics influence peri-implant disease. MATERIAL AND METHODS: A search of PubMed and The Cochrane Library of the Cochrane Collaboration (CENTRAL) as well as a hand search of articles were conducted. Publications and articles accepted for publication u…

The Spring 2015 issue of the International Journal of Telerehabilitation (IJT) contains original research that analyzes provider perspectives on the use of telepractice to serve the families of children who are deaf or hard of hearing. Two case studies examine the utility of administering Facial Affect Training through…

OBJECTIVES: The purpose of this systematic review was to evaluate if articaine has better efficacy as compared to lignocaine when used for infiltration anaesthesia for primary molar extractions. METHODS: The electronic databases of PubMed, Embase, Scopus, BioMed Central, CENTRAL, and Google Scholar were searched up to…